Camptosar irinotecan package insert

Author: ihjc

August undefined, 2024

Reference ID: 3965252 - Food and Drug Administration

WebTrade Name: CAMPTOSAR; CAMPTO Chemical Family: Mixture Intended Use: Pharmaceutical product used as Antineoplastic 2. HAZARDS IDENTIFICATION ... Irinotecan Hydrochloride 100286-90-6 Not Listed Mut. Cat.3;R68 Repr. Cat.3;R61 Xn;R22 2% Sodium hydroxide 1310-73-2 215-185-5 C;R35 ** Web3. How to use Irinotecan 4. Possible side effects 5. How to store Irinotecan 6. Contents of the pack and other information 1. What Irinotecan is and what it is used for Irinotecan hydrochloride 20 mg/ml concentrate for solution for infusion is an anticancer medicine containing the active substance irinotecan hydrochloride trihydrate. biogeographical floral provinces

CAMPTOSAR® (irinotecan HCl) Pfizer Medical …

WebCAMPTOSAR (irinotecan hydrochloride) Injection is available as a sterile, pale yellow, clear, aqueous solution in a vial packaged within a carton in the following packaging configurations: Single-dose amber colored … WebMar 18, 2009 · Camptosar (irinotecan) package insert. Japan: Yakult Honsha Co, LTD and Daiichi Pharmaceutical Co, LTD; 2007. 20. Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. NEJM. 2000;343:905-914. 21. Saltz LB, Niedzwiecki D, Hollis D, et al. Irinotecan fluorouracil … WebIRINOTECAN Hydrochloride Injection, USP* Brand Name Equivalent: CAMPTOSAR®(CAMPTOSAR is a registered trademark of Yakult Honsha Company, Ltd.) Therapeutic Category: Antineoplastic Agent PreventIV Measures®Features: Easy-to-read drug name and dosage strength to aid in identifying the right product biogeographical classification of india ppt

Irinotecan (Camptosar) HemOnc.org - A Hematology Oncology …

WebCAMPTOSAR Injection (irinotecan hydrochloride injection) is an antineoplastic agent of the topoisomerase I inhibitor class. CAMPTOSAR is supplied as a sterile, pale yellow, clear, aqueous solution. Each... Read more Did you find an answer to your question? Yes No 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action WebView Fresenius Kabi's Oncology Product Portfolio including Irinotecan Hydrochloride Injection – cross references to branded drug Camptosar®. ... Cross references to branded drug Camptosar ® 100 mg per 5 mL Order. Package Insert Download NDC No. 63323-193-55 Product No 109355 Description SD Amber Vial ... daily amount of saturated fat recommendedWebHow Irinotecan Is Given: This medication is given by infusion through a vein (intravenously, IV). There is no pill form of this medication. Irinotecan is an irritant. An irritant is a chemical that can cause inflammation of the vein through which it is given. If the medication escapes from the vein it can cause tissue damage. biogeographically

"WebIrinotecan hydrochloride trihydrate, CPT -11 COMMON TRADE NAME(S): CAMPTOSAR® CLASSIFICATION: Topoisomerase I inhibitor. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. MECHANISM OF ACTION: Irinotecan is a semisynthetic, water -soluble derivative of camptothecin, which is a cytotoxic alkaloid ... " - Camptosar irinotecan package insert

Camptosar irinotecan package insert

CAMPTOSAR® Highlights (irinotecan HCl) Pfizer Medical …

WebIrinotecan (Camptosar) patient drug information (UpToDate) History of changes in FDA indication 6/14/1996: Initial accelerated approval for the treatment of patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following 5 … WebThe concentrate contains 20 mg/ml irinotecan hydrochloride trihydrate (equivalent to 17.33 mg/ml irinotecan). Excipients: sorbitol, lactic acid and water for injections. The pH of the solution is adjusted to 3.5 with sodium hydroxide. Vials of CAMPTO contain 40 mg or 100 mg or 300 mg of irinotecan hydrochloride trihydrate. THERAPEUTIC INDICATIONS

Did you know?

WebSep 26, 2024 · Camptosar Dosage Generic name: IRINOTECAN HYDROCHLORIDE 20mg in 1mL Dosage form: injection, solution Drug class: Miscellaneous antineoplastics Medically reviewed by Drugs.com. Last updated on Sep 26, 2024. Colorectal Cancer Combination Regimens 1 and 2 Administer CAMPTOSAR as a 90-minute intravenous … WebCamptosar (irinotecan) dosing, indications, interactions, adverse effects, and more Drugs & Diseases irinotecan (Rx) Brand and Other Names: Camptosar Classes: Antineoplastics, Topoisomerase...

WebSep 6, 2024 · CAMPTOSAR should be administered as an intravenous infusion over 90 minutes. CAMPTOSAR Injection must be diluted prior to infusion. CAMPTOSAR should be diluted in 5% Dextrose Injection, USP, (preferred) or 0.9% Sodium Chloride Injection, USP, to a final concentration range of 0.12 to 2.8 mg/mL. WebApr 1, 2024 · US Brand Name Camptosar Novaplus Irinotecan Hydrochloride Descriptions Irinotecan injection is given together with other medicines (eg, 5-fluorouracil, leucovorin) to treat patients with metastatic cancer (a cancer that …

WebMay 11, 2024 · CAMPTOSAR is indicated for patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. 2 DOSAGE AND ADMINISTRATION 2.1 Colorectal Cancer Combination Regimens 1 and 2. Administer CAMPTOSAR as a 90-minute intravenous infusion … WebMar 21, 2024 · Irinotecan (Camptosar ©, CPT-11), a topoisomerase I inhibitor, is a commonly used cytotoxic chemotherapeutic in the treatment of multiple malignancies, particularly of gastrointestinal origin. Dysarthria secondary to irinotecan has been described as a rare side effect in a few case reports with limited data to recommend appropriate …

Webcombination with leucovorin and oxaliplatin or irinotecan, is 400 mg/m. 2. by intravenous bolus on Day 1, followed by 2400 mg/m. to 3000 mg/m. 2. intravenously as a continuous infusion over 46 hours every two weeks. The recommended dose of fluorouracil, if administered in a bolus dosing regimen in combination with leucovorin, is 500 mg/m

WebThe CAMPTOSAR (irinotecan) package insert recommends a reduced initial dose be considered for patients homozygous for the UGT1A1*28 allele and are at an increased risk for neutropenia following initiation of CAMPTOSAR treatment. AutoGenomics Doc EM-34028E (English) Rev. I (CO 4027) May 2024 biogeographic isolation quizWebJ9206 – Injection, irinotecan, 20 mg: 1 billable unit = 20mg NDC: Camptosar 40 mg/2 ml single-dose vial – 00009-7529-xx Camptosar 100 mg/5 ml single-dose vial – 00009-7529-xx Camptosar 300 mg/15 ml single-dose vial – 00009-7529-xx VII. References biogeographical meaningWebIn addition, homozygosity for *28 is specified as the primary risk factor in the Camptosar (irinotecan) package insert. 29 Consequently, we chose to limit the review of clinical validity to these ... biogeographical patternsWebIrinotecan hydrochloride (HCL) is an antineoplastic drug that is a semisynthetic derivative of camptothecin, an alkaloid extract from plants. The drug works by causing strand breaks in DNA that the cell cannot repair leading to cell death. Irinotecan is FDA approved for the following indications: daily amount of protein per dayWebMay 11, 2024 · CAMPTOSAR is indicated for patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. 2 DOSAGE AND ADMINISTRATION 2.1 Colorectal Cancer Combination Regimens 1 and 2 Administer CAMPTOSAR as a 90-minute intravenous infusion … daily amount of sodium for women biogeographical realmsWebThe CAMPTOSAR (irinotecan) package insert recommends a reduced initial dose be considered for patients homozygous for the UGT1A1*28 allele and are at an increased risk for neutropenia following initiation of CAMPTOSAR treatment. AutoGenomics Doc EM-34028E (English) Rev. K (CO 4180A) Feb. 2024 biogeographical evidence