WebMar 22, 2024 · Alexander disease is characterized by degenerative changes of the white matter of the brain caused by a lack of normal amounts of myelin. The disorder is also associated with the formation of abnormal, fibrous deposits known as “Rosenthal fibers” in the astrocytic processes around small blood vessels and astrocytic cell bodies in certain ... WebJan 31, 2024 · Demyelinating disorders are a subgroup of white matter disorders characterized by the destruction or damage of normally myelinated structures. These disorders may be inflammatory, infective, …
White Matter Hyperintensities on Magnetic Resonance Imaging: …
WebGenetic and acquired disorders of white matter comprise a diverse group of conditions, with often overlapping clinical and radiological findings. Patients present with a variable combination of cognitive impairment, ataxia, … WebWhite matter lesions representing ischemic demyelination have evolved in terms of our understanding of their pathogenesis and potential clinical significance. Low density … how can you be a good person
"What is chronic microvascular ischmic changes and demyelinating ...
WebFeb 17, 2024 · Changes in these directional diffusivities reflect white matter integrity and the underlying pathology [9,10,11,12]. Specifically, demyelination results in an increased RD, presumably due to the loss or disruption of myelin membrane integrity that hinders water diffusion perpendicular to axonal tracts [ 11 , 13 , 14 ]. WebPatterns of longitudinal change in the normalized magnetization transfer ratio and DTI radial diffusivity in slowly expanding/evolving lesions were consistent with progressive … WebLeukodystrophies are a group of rare neurological ( nervous system) diseases. They affect the white matter in the brain and spinal cord. White matter is tissue made of insulated nerve fibers. Leukodystrophies target myelin, which is the protective insulation covering nerve cells. Without myelin, nerves can’t communicate well. how can you be an ethical communicator