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Web12 apr. 2024 · Gene deletion and heterologous expression led to the identification of the responsible five-gene spe cluster for the speradine skeleton formation. The highly oxygenated indole alkaloid speradine F (4) with a 6/5/6/5/5/5 hexacyclic skeleton was isolated from a culture of Penicillium palitans, together with its precursors β-cyclopiazonic … Web29 mrt. 2024 · Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release. Zhu Y, Li M, Wang X, Jin H, Liu S, Xu J, Chen QZhu Y, et al. Cell Res, 2012 Jan. PMID 21577235; Assignment of the gene for the cytochrome c1 subunit of the mitochondrial cytochrome bc1 complex (CYC1) to human chromosome … Web10 feb. 2024 · 8IBU, 8IBV. PubMed Abstract: Motilin is an endogenous peptide hormone almost exclusively expressed in the human gastrointestinal (GI) tract. It activates the motilin receptor (MTLR), a class A G protein-coupled receptor (GPCR), and stimulates GI motility. To our knowledge, MTLR is the first GPCR reported to be activated by macrolide … sifd rainbow chest mod