Stard3 cholesterol
WebbThe rate-limiting stage of steroidogenesis is cholesterol delivery to the inner ... and its steroidogenic role is carried out by STARD3, which can also transfer cholesterol for initiating ... WebbSTARD3 Polyclonal Antibody, Invitrogen™-Rabbit Polyclonal Antibody Kaufen Sie STARD3 Polyclonal Antibody, Invitrogen™ bei Fishersci.de
Stard3 cholesterol
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WebbIn terms of cholesterol trafficking, it has been reported that the START domain 3 (StARD3, steroidogenic acute regulatory protein-related lipid transfer domain-3) creates … Webb5 jan. 2024 · Since STARD3 knock-out mice have no phenotype , it is thought that in normal tissues, STARD3 function is balanced by other homeostatic mechanisms regulating cholesterol distribution. Consistent with this idea, silencing STARD3 by siRNAs in HeLa cells (an endometrium HER2-negative cancer cell line) has no impact on viability and cell …
WebbORCID 0000-0002-9522-9726 Correu electrònic tebar ub.edu Departament Departament de Biomedicina Endocitosi, tràfic i senyalitzacio Webb20 okt. 2024 · Abstract. STARD1 moves cholesterol (CHOL) from the outer mitochondrial membrane (OMM) to the inner membrane (IMM) in steroidogenic cells. This activity is …
Webb18 sep. 2024 · 2. The Role of Intracellular Cholesterol in Cancer Development Several studies indicated the association between cholesterol levels and cancer devel-opment … WebbAnti-MLN64/STARD3 Antibody, clone 2BE-2F4 ascites fluid, clone 2BE-2F4, from mouse; Synonyms: StAR-related lipid transfer protein 3, MLN64/STARD3, Metastatic lymph node gene 64 protein, MLN 64, Protein CAB1, START domain-containing protein 3, StARD3; find Sigma-Aldrich-MABS1283 MSDS, related peer-reviewed papers, technical documents, …
Webb18 sep. 2024 · As STARD3 is a key protein in the cholesterol movement in cancer cells, it is of interest to identify inhibitors able to block its activity. Cancer is one of the major … christmas music youtube rnbWebbStarD1, which is known to distribute cholesterol to the dria (17), and StarD3, which appears to mediate ER-to-n o h c o t i m endosome cholesterol transport (18), the function of … get fathers military recordsWebb1 jan. 2014 · The cloning of STARD3 was fairly rapid and easy; the functional characterization of this protein has been difficult and is far from being achieved. To date, an understanding of how STARD3 handles cholesterol has been elusive. From its homology with STARD1, it was proposed that STARD3 functions to transport cholesterol … get fatmoon creativeWebbSTARD3 was isolated in the early 1990s in a study aimed at finding new genes implicated in breast cancer. The function of the STARD3 gene, referred to at that time as Metastatic … christmas music youtube popWebbIn this work, we showed that STARD3 and its ER–resident partner, VAMP–associated protein (VAP), assemble into a machine that allows a highly efficient transport of … get fast twitter followersWebb1 jan. 2024 · STARD3 is necessary for cholesterol transfer and metabolism in tumor cells. The possible role played by STARD3 as a diagnostic and prognostic biomarker was … get fast muscle growthWebb11 nov. 2024 · Two major key players are the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR), catalyzing the rate-limiting step in cholesterol synthesis ( Geelen et al., 1986 ), and the low-density lipoprotein (LDL) receptor ( Yokoyama et al., 1993 ), binding the major cholesterol-carrying lipoprotein. get fast wifi net