Sublytic 意味
Web结果发现,过表达GCN5能提高Cyclin D1的启动子活性、mRNA和蛋白水平,而沉默GCN5基因则能降低由sublytic C5b⁃ 9刺激导致的Cyclin D1基因的启动与表达。. 提示, GCN5确能促进Cyclin D1基因的表达。. 文献报道,GCN5作为一个兼有HAT活性的转录辅激活因子,其表达升高时既能 ... Web19 Mar 2014 · In the present study, human brain microvascular endothelial cells (hBMECs) were treated with non-cytotoxic and sublytic concentrations of the culture supernatant of S. suis serotype 2 strain 05ZYH33 and stained with FITC-labeled phalloidin at different time points after challenging the culture with sublytic supernatant. Fluorescence microscopy …
Sublytic 意味
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Web「Subarctic」の意味・翻訳・日本語 - 亜北極の、北極に近い|Weblio英和・和英辞書 Subarctic: 亜北極の,北極に近い 英和辞典・和英辞典 http://jnmu.njmu.edu.cn/zr/aumn/article/html/aumn210202
Web1 Sublytic membrane attack complex drives glycolysis and mitochondrial 2 dysfunction with inflammatory consequences in human monocyte-derived 3 macrophages 4 Gisela Jimenez-Duran1,2, ... Web「subtlety」の意味・翻訳・日本語 - 微妙、名状しがたいこと、細かい区別立て、微妙な点、鋭敏、敏感、巧みさ、巧妙|Weblio英和・和英辞書 subtlety: 微妙,名状しがたいこと, …
Web11 Jun 2024 · It has been confirmed that rat Thy‐1N is complement‐dependent, particularly sublytic C5b‐9‐dependent.9, 10 Our early studies have disclosed that sublytic C5b‐9 stimulation in vitro can induce rat GMC proliferation and ECM secretion.11, 12 But, the underlying mechanism of sublytic C5b‐9‐triggered GMC proliferative pathological … WebMeaning of sublytic for the defined word. 文法的に、この単語"sublytic"は 形容詞です。また形態素、より具体的に、プレフィックスです。
Web7 Dec 2016 · Here, we also demonstrate that p300 expression was increased in vitro, with both mRNA and protein levels peaked at 3 h (Supplementary Figure S4A and B), and sublytic C5b-9 as well as Thy-1 Ab + C6DS + C6 significantly enhanced p300 level in GMCs than other treatments (Supplementary Figure S4C, D), further confirming that p300 elevation was …
Webafter sublytic C5b-9 attack.9 Generally, the injury by C5b-9 to nucleated cells is almost non-lysis (sublytic) because the surfaces of the cells have many homologous restriction … estás hechoWeb2 Sep 2013 · Sublytic complement activation, which can result from a low level of antibody or low antigen expression, results in increased activation of the PI3K/AKT survival pathway and accelerated tumor growth. This can be eliminated by treatment with PI3K inhibitors such as NVP-BEZ235 and Wortmannin, which also increase the efficacy of even high doses of … hb menu dsiWeb结论:Sublytic C5b-9能够诱导GMCs合成Tsp-1、TGF-β_1,促进GMCs增殖和ECM分泌,其ECM的分泌可能与Tsp-1、TGF-β_1的合成有一定的关系。 第二部分沉默Pi3-k/Akt基因对sublytic C5b-9促进GMCs合成Tsp-1,TGF-β_1及其细胞增殖和ECM分泌的影响 目的:从基因水平上探讨沉默磷脂酰肌醇3 ... hbmenu dsWeb16 Dec 2013 · The increased production of interleukin 6 (IL-6) and transforming growth factor β1 (TGF-β1) by glomerular mesangial cells (GMCs) in rat Thy-1 nephritis (Thy-1N), a model of human mesangioproliferative glomerulonephritis, is accompanied by sublytic C5b-9 deposition, but the mechanism of IL-6 and TGF-β1 upregulation in rat GMCs triggered by … hbmenu daybreakWeb17 Aug 2024 · Sublytic MAC stimulation skews hMDM metabolism towards glycolysis. Since both our metabolomics and proteomics studies indicated enhanced glycolysis as well as … hbmenu是什么Web1 Feb 2003 · The complement system consists of >30 proteins that interact in a carefully regulated manner to destroy invading bacteria and prevent the deposition of immune complexes in normal tissue. This complex system can be activated by diverse mechanisms proceeding through distinct pathways, yet all converge on a final common pathway in … hb menu italianoWebincluding sublytic C5b‐9.15‐17 At the initial stage of our experiments it was found that RGC‐32 expression was up‐regulated both in the renal tissues of Thy‐1N rats (in vivo) and in the GMCs stimulated with sublytic C5b‐9 (in vitro). However, the functions of RGC‐32 in sublytic C5b‐9‐mediated GMC proliferation and ECM ... hb menurun karena